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Loperamide : Interaction with Foods, Herbs & Alcohol


Are you taking Loperamide? Are you aware of the dangers of combining Loperamide with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Loperamide Interactions with Food and Herbs

Grapefruit juice: Avoid taking Grapefruit juice with Loperamide as it may increase the risk of change in heart rhythm or heartbeat (1 Trusted Source
Loperamide can kill: A rising trend amidst the opioid epidemic

Go to source
).
Valerian: Concurrent use of Valerian and Loperamide may result in delirium with symptoms of confusion, agitation, and disorientation.
St.John’s wort: Taking St. John’s wort and Loperamide together may result in delirium with symptoms of confusion, agitation, and disorientation (2 Trusted Source
Herb-drug interactions: Review and assessment of report reliability

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).

Loperamide Interactions with Alcohol

Drinking alcohol with Loperamide may have side effects like feeling sleepy or dizzy and having difficulty in concentrating (3 Trusted Source
Loperamide: Drug Information

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).

When and How to Take Loperamide

  • Loperamide is available in the form of a tablet, capsule, suspension or oral solution.
  • Non-prescription loperamide is taken immediately after each loose bowel movement but not for more than 24-hours.
  • Prescription Loperamide can be taken one or more times in a day.
  • Take Loperamide with a glass full of water.
  • Paediatric dose is different from adult dose.
  • Loperamide should not be given to children less than 2 years old.
  • When taking loperamide liquid solution, you should use a measuring cup instead of spoons (4 Trusted Source
    Loperamide: Medlineplus Drug Information

    Go to source
    ).

References

1.Loperamide can kill: A rising trend amidst the opioid epidemic
https://journal.chestnet.org/action/showPdf?pii=S0012-3692%2818%2931948-2
2.Herb-drug interactions: Review and assessment of report reliability
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014604/pdf/bcp0052-0587.pdf
3.Loperamide: Drug Information
https://www.nhs.uk/medicines/loperamide/#:~:text=It's%20best%20not%20to%20drink,dizzy%20and%20having%20difficulty%20concentrating.
4.Loperamide: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a682280.html

Drug Name : Loperamide

Loperamide is an antidiarrheal agent, prescribed for diarrhea.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.


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