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Food and Herbs Interaction with Efavirenz


Are you taking Efavirenz ? Are you aware of the dangers of combining Efavirenz with certain foods and herbs? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Efavirenz Interactions with Food and Herbs

High-fat meals:When Efavirenz is taken with a high-fat meal, which increases the blood level of the medication, it can lead to potentially dangerous side effects (1 Trusted Source
SUSTIVA (Efavirenz) capsules

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).

St. Johns Wort: Taking St. John's wort may lower Efavirenz levels, resulting in increased viral load and possible drug resistance or cross-resistance to other antiretroviral drugs (1 Trusted Source
SUSTIVA (Efavirenz) capsules

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).

When and How to Take Efavirenz

  • Efavirenz is available in the form of a capsule and a tablet to be taken orally.
  • It is usually taken once a day on an empty stomach with water (at least 1 hour before or 2 hours after a meal).
  • Swallow the tablets and capsules as a whole instead of crushing, chewing or breaking them.
  • Follow the directions exactly as given on the prescription label.
  • Take the medication at the same time every day for better results.
  • Do not exceed or skip a dose. If you miss it, take the medication as soon as you remember.
  • Do not double the dose at a time to compensate for a missed dose (2 Trusted Source
    National Library of Medicine: Efavirenz MedlinePlus Drug Information.

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    ).

References

1. SUSTIVA (Efavirenz) capsules https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/20972s13lbl.pdf
2. National Library of Medicine: Efavirenz MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a699004.html#

Drug Name : Efavirenz

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and active antiretroviral therapy (HAART) prescribed for the treatment of human immunodeficiency virus (HIV) type 1 either alone or with other medications.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.


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