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Clorazepate : Interaction with Foods, Herbs & Alcohol

Last Updated on Jul 17, 2023

Are you taking Clorazepate? Are you aware of the dangers of combining Clorazepate with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication. 
Clorazepate is a benzodiazepine derivative, prescribed for anxiety.
Clorazepate comes as a tablet and capsule to take by mouth, with or without food. It's essential to follow the directions on the prescription label and not take more than the recommended dosage. Familiarize yourself with how and when to take Clorazepate for maximum benefit.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.

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Clorazepate Interactions with Food and Herbs

Ginkgo biloba and St.John's Wort: Clorazepate may interact with Ginkgo biloba and St. John's wort.The combination of these herbs with clorazepate should therefore be avoided.

Periwinkle: The interaction of clorazepate with vinpocetine, which is a derivative of periwinkle (Vinca species), may actually be beneficial. However, further studies are needed to prove the interaction.

Clorazepate Interactions with Alcohol

Alcohol adds to the effect of clorazepate on the central nervous system resulting in excessive drowsiness and decreased motor skills.
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When and How to Take Clorazepate

Clorazepate comes as a tablet to take by mouth. You may take it one to three times a day. Stick to the recommended dose. If you take clorazepate to treat anxiety, your doctor will prescribe a low dose initially and will increase it gradually. If you take it for alcohol withdrawal, your doctor will start you on a high dose and then gradually decrease the dose.
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Clorazepate for Medical Condition(s)

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