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Melitracen is prescribed to treat depression and anxiety.

It is also available as a combination drug along with flupentixol which is indicated for different types of depression (psychogenic, masked, menopausal, in alcoholics), depressive neuroses, psychosomatic affections accompanied by anxiety and apathy, and dysphoria in alcoholics. It is also given as a maintenance dose in psychogenic depressions and other psychoses.

Melitracen comes under the category of tricyclic antidepressants (TCAs) which act by decreasing re-uptake of neurotransmitters like norepinephrine and serotonin at the nerve synapse. This causes a high concentration of the neurotransmitters in the next neuron causing an antidepressant effect. Melitracen acts similarly as other TCAs regarding efficacy against depression and anxiety. It has an added advantage of improved tolerability and a slightly faster onset of action.  

Drug information on Moody (10+0.5) (Flupenthixol) from Cure Quick Remedies

Moody (10+0.5)

  Tablet  
Cure Quick Remedies
Generic : Melitracen
 48.00
0.5mg/10mg
10 Tablets
Combination of Generics : Melitracen, Flupenthixol
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Side effects of Melitracen

Rare in the recommended doses


  Central nervous system: A headache, drowsiness, anxiety, insomnia 

  Gastrointestinal: Dry Mouth, weight gain, nausea, upset stomach, decreased appetite, diarrhea

  Ophthalmological: Blurred vision

  Others: Weakness, difficulty in breathing, sweating 


Side-effects of the combination drug:


  Central nervous system: Restlessness, insomnia, hypomania, dizziness, tremor, visual disturbances, headache, extrapyramidal symptoms

  Others: Hyperprolactinemia

When is Melitracen not to be taken? (Contraindications)

Melitracen is contraindicated in patients with

• Hypersensitivity to the drug
• Myocardial infarction
• Narrow-angle glaucoma
• Bipolar disorder
Epilepsy
• Who received monoamine oxidase inhibitors (MAOI) within two weeks

For those using the combination drug, it is contraindicated in patients:
• In the immediate recovery phase after myocardial infarction
• With defects in bundle-branch conduction
• With untreated narrow-angle glaucoma
• With acute alcohol, barbiturate and opiate intoxications
• Who received monoamine oxidase inhibitors (MAOI) within two weeks

The combination is not recommended for excitable or overactive patients since its activating effect may excite them more.


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