Drug information on Toldin (400 mg) (Etodolac) from Torrent Pharmaceuticals Ltd.

Medical Condition(s) for which Toldin (400 mg) may be prescribed

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•  Gastrointestinal: Constipation, diarrhea, nausea, stomach upset, severe vomiting, ulcers and bleeding, heart burn.

•  Central Nervous System: Dizziness, seizures, severe headache, unusual tiredness or weakness.

•  Skin: Rash, itching, hives, blistered, peeling skin, unusual bruising or bleeding.

•  Eye and ENT: Stuffy nose, blurred vision, vision or speech changes, ringing in the ears.

•  Respiratory: Difficulty in breathing, shortness of breath.

•  Hypersensitivity: Swelling of the mouth, face, lips, or tongue, hands, leg.

•  Heart: Tightness in the chest.

•  Miscellaneous: Sudden or unexplained weight gain, unusual joint or muscle pain.

Osteoarthritis; Rheumatoid arthritis- 600-1,000 mg/day. Acute pain 200-400 mg 6-8 hourly. Max: 1 g/day.

This medication is available in the form of tablet, and capsules to take by mouth with food. Take tablets and capsules two or three times per day, extended-release tablet once in a day.

Peptic ulcer, hypersensitivity to this drug/NSAIDs, perioperative pain in patients who have undergone coronary artery bypass graft.

• It is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID in it too.

• Caution needed for patients with history of heart diseases, dehydration, impaired kidney, liver function, asthma, nasal polyps, gastrointestinal disease, elderly, patients receiving anticoagulant, pregnancy, breastfeeding, and in children.

•Serious stomach ulcers or bleeding can occur. Avoid in high doses or for a long time, smoking, or drinking alcohol they may increase the risk of these side effects.

Taking this medication with food will not reduce the risk of these effects.

Store at 68° to 77°F. Store it in airtight container.