This medication is a BRAF enzyme inhibitor, prescribed for malignant melanoma. It slows or stops the spread of cancer cells.
PO- The recommended dose is 960 mg (four 240 mg tablets) twice daily.
It comes as a tablet to take by mouth, with or without food.
• Caution should be exercised in patients with history of history of heart problems, irregular heartbeat, liver or kidney impairment, skin cancer, low blood electrolyte levels, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
• It may cause dizziness, tiredness, weakness, or blurred vision, do not drive a car or operate machinery while taking this medication.
• Avoid exposure to sunlight; otherwise it may cause sunburn easily.
• Monitor electrocardiograms (ECGs), liver function, eye exams, blood electrolyte levels, and skin evaluations regularly while taking this medication.
• Most Common :
Joint pain, rash, hair loss, fatigue, photosensitivity reaction, nausea, itching, and skin papilloma.
• Skin : Palmar-plantar erythrodysaesthesia syndrome, keratosis pilaris, erythema nodosum, Stevens-Johnson syndrome.
• Musculoskeletal : Joint inflammation.
• Central Nervous System : Dizziness, nerve disease, paralysis.
• Neoplasms : Cutaneous Squamous Cell Carcinoma.
• Metabolic : Weight decreased.
• Eye : Retinal vein occlusion, eye inflammation.
• Heart : Abnormal heart rhythm.
Avoid excess dosage.
Store it at room temperature (20°C - 25°C).
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