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General Information on Vandetanib

Generic Name : Vandetanib

Pronunciation : van-DET-a-nib

Latest prescription information about Vandetanib. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Vandetanib

International- Caprelsa.

Why is Vandetanib Prescribed? (Indications)

This medication is a kinase inhibitor, prescribed for medullary thyroid cancer. It blocks the action of an abnormal protein that signals cancer cells to multiply.

When should Vandetanib not to be taken? (Contraindications)

Contraindicated in patients with congenital long QT syndrome.

What is the dosage of Vandetanib?

PO- The recommended daily dose is 300 mg.

How should Vandetanib be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Vandetanib?

Caution should be exercised in patients with history of heart disease, irregular heartbeat, heart attack, liver or kidney impairment, lung or breathing problems, bleeding episodes, high blood pressure, abnormal blood electrolyte, underactive thyroid, skin disease, diarrhea, decrease in white blood cell levels and platelet levels; who are taking other medications, any allergy, during pregnancy and breastfeeding.

It may cause tiredness, weakness, or blurred vision, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

It may reduce platelet counts; avoid injury or bruising.

Avoid exposure to sunlight.

Monitor ECGs, liver, thyroid, and kidney function; blood pressure, blood sugar, blood electrolyte levels and complete blood cell counts regularly while taking this medication.

What are the side effects of Vandetanib?

   Most Common : Diarrhea, rash, acne, nausea, high blood pressure, headache, fatigue, decreased appetite, and abdominal pain.
   Skin : Dry Skin, photosensitivity, itching.
   Gastrointestinal : Vomiting, indigestion, decreased weight.
   Central Nervous System : Weakness, sleeplessness, depression, tiredness, weakness.
  Serious Effects: QT prolongation.

What are the other precautions for Vandetanib?

Avoid excess dosage.

What are the storage conditions for Vandetanib?

Stored it at room temperature (25C).

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