Information about Regorafenib
Generic Name : Regorafenib
Latest prescription information about Regorafenib. Learn its indications, dosage, how to take, when to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Trade Names/Brand Names of Regorafenib
Why is Regorafenib Prescribed? (Indications)
This medication is a kinase inhibitor, prescribed for metastatic colorectal cancer (CRC) in patients who have been previously treated with fluoropyrimidine- oxaliplatin-and irinotecan-based chemotherapy. It works by helping to stop cancer cells from growing.
What is the dosage of Regorafenib?
PO- The recommended dose is 160mg, once daily for the first 21 days of each 28-day cycle.
How should Regorafenib be taken?
It comes as a tablet to take by mouth with food.
What are the warnings and precautions for Regorafenib?
• Caution should be exercised in patients with history of bleeding problems, high blood pressure, heart, liver, or kidney diseases, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Avoid drinking grapefruit juice while taking this medication.
• Patient may develop with increased risk of Reversible Posterior Leukoencephalopathy Syndrome (RPLS). If it is so consult with your doctor immediately.
What are the side effects of Regorafenib?
• Most Common:
Weakness, fatigue, decreased appetite and food intake, Hand-foot skin reaction (HFSR) (palmar-plantar erythrodysesthesia [PPE]), diarrhea, weight loss, and infection.
• General :
• Metabolic :
Anemia, weight loss.
• Skin :
• Gastrointestinal :
• Heart :
High blood pressure, bleeding.
• Respiratory :
Difficulty in breathing.
What are the other precautions for Regorafenib?
Avoid excess dosage.
What are the storage conditions for Regorafenib?
Store it at controlled room temperature (15 to 30°C).