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Probenecid - Indications, Dosage, Side Effects and Precautions

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Information about Probenecid

Generic Name : Probenecid
Up-to-date prescription details regarding Probenecid are provided here.

Pronunciation : proe ben' e sid

Learn the correct pronunciation of the Probenecid, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Therapeutic Classification : Gout Therapy

Trade Names/Brand Names of Probenecid

India :

International :


Benemid

Why is Probenecid Prescribed? (Indications)

This medication is a uricosuric agent, prescribed for chronic gout and gouty arthritis. It increases the excretion of uric acid from the body.

When should Probenecid not be taken? (Contraindications)

Contraindicated in children under 2 years of age, persons with known blood dyscrasias, kidney stone, hypersensitivity, during pregnancy and breastfeeding.

What is the dosage of Probenecid?

PO- The usual adult dose for hyperuricemia is 500 mg twice daily and the maximum dose is 2 grams daily.

How should Probenecid be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Probenecid?

• Caution should be exercised in patients with history of ulcers, kidney stones,kidney disorder, blood disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may affect blood sugar level, monitor sugar level regularly.

What are the side effects of Probenecid?

Central Nervous System - Headache and dizziness.
Metabolic - Precipitation of acute gouty arthritis.
Gastrointestinal - Liver damage, vomiting, nausea, loss of appetite and sore gums.
Genitourinary - Kidney damage, blood in urine, kidney stone, back pain and urinary frequency.
Hypersensitivity - Shock, fever, hives and itching.
Blood - Anemia and decrease in white blood cells.
Skin - Skin inflammation, hair loss and flushing.

What are the other precautions for Probenecid?

Drink adequate fluid especially during the first few months of treatment.

What are the storage conditions for Probenecid?

Store it at room temperature (20°-25°C).
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