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Pralidoxime - Indications, Dosage, Side Effects and Precautions

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Information about Pralidoxime

Generic Name : Pralidoxime
Up-to-date prescription details regarding Pralidoxime are provided here.

Pronunciation : PRAL i DOX eem

Learn the correct pronunciation of the Pralidoxime, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y57.2 Therapeutic Classification : Anticholinesterase Antidote

Trade Names/Brand Names of Pralidoxime

India :

International :


Protopam Chloride

Why is Pralidoxime Prescribed? (Indications)

This medication is an antidote, prescribed for organophosphorous poisoning. But is not effective as an antidote for all types of pesticide poisonings.

When should Pralidoxime not be taken? (Contraindications)

Contraindications in patients with known hypersensitivity to the drug and Carbamate pesticide poisoning.

What is the dosage of Pralidoxime?

Adult: IV/IM- Used in combination with atropine. The recommended dose is 1-2 g, repeat dose after 1 hour, then 8-12 hourly if needed.

How should Pralidoxime be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein, muscle or under the skin.

What are the warnings and precautions for Pralidoxime?

• Caution should be exercised in patients with history of myasthenia gravis, kidney disease, during pregnancy and breastfeeding.

• Monitor breathing, blood pressure, oxygen levels, kidney function regularly while taking this medication.

• It may cause drowsiness, blurred vision, or dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Pralidoxime?

Most Common - Blurred vision, double vision, impaired accommodation, dizziness, headache, drowsiness, nausea, muscle weakness, and fast heart rate.

What are the other precautions for Pralidoxime?

Avoid excess dosage.

What are the storage conditions for Pralidoxime?

Store it at room temperature (20°-25°C).
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