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Interferon Gamma 1B - Indications, Dosage, Side Effects and Precautions

Written by Anushta Chandrapalan, M.Sc  | Medically Checked by S. Hemamalini, B. Pharm
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Information about Interferon Gamma 1B

Generic Name : Interferon Gamma 1B
Up-to-date prescription details regarding Interferon Gamma 1B are provided here.
Pronunciation :  IN-ter-FEER-on GAM-uh
Learn the correct pronunciation of the Interferon Gamma 1B, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Interferon Gamma 1B

International- Act immune.

Why is Interferon Gamma 1B Prescribed? (Indications)

This medication is a protein, prescribed for reducing the repeated occurrences and severity of serious infections associated with chronic granulomatous disease. 

When should Interferon Gamma 1B not be taken? (Contraindications)


What is the dosage of Interferon Gamma 1B?

SC- For patients whose body surface area is greater than 0.5 m2: The recommended dose is 50 mcg/m2 (1 million IU/m2), three times weekly.
For patients whose body surface area is equal to or less than 0.5 m2- The recommended dosage is 1.5 mcg/kg/dose, three times weekly.

How should Interferon Gamma 1B be taken?

It comes as a solution for injection to be administered by a healthcare provider under the skin.

What are the warnings and precautions for Interferon Gamma 1B?

• Caution should be exercised in patients with history of bone marrow depression, anemia, liver impairment, epilepsy, suicidal thoughts, irregular heartbeat, congestive heart failure, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may reduce platelet counts; avoid injury or bruising.

Monitor complete blood cell counts, kidney and liver functions regularly while taking this medication.

Avoid contact with people who have infections.

What are the side effects of Interferon Gamma 1B?

   Most Common : Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting, nausea and muscle/joint pain.
   Heart : Low blood pressure, fainting, fast heart rate, heart block, heart failure and heart attack.
   Central Nervous System : Confusion, disorientation, gait disturbance, Parkinsonian symptoms, seizure, hallucinations and stroke.
   Gastrointestinal : Liver impairment, gastrointestinal bleeding and inflammation of pancreas.
   Blood : Blood clot events such as deep venous thrombosis and pulmonary embolism.
   Metabolic : Increased level of blood sugar and cholesterol.
   Respiratory : Fast breathing, asthma and lung inflammation.
   Genitourinary : Reversible kidney insufficiency.
   Others : Chest discomfort and exacerbation of skin patches.

What are the other precautions for Interferon Gamma 1B?

Avoid excess dosage.

What are the storage conditions for Interferon Gamma 1B?

Store it in refrigerator (2-8C).

Last Updated : August 11, 2022

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