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Ifosfamide - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Ifosfamide

Generic Name : Ifosfamide
Pronunciation : eye fos' fa mide
Latest prescription information about Ifosfamide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Ifosfamide

India : 

International : 

Holoxan Inj, Holoxan-Uromitexan Vial, Ifex-M Inj, Ifex-M Vial, Ifocip Inj, Ifoxan With Mesna Inj Combi-Pack, Ipamide Inj, Isoxan Combipackvial

Why is Ifosfamide Prescribed? (Indications)

This medication is an antineoplastic agent, prescribed for certain types of cancer (breast cancer, lymph cancer, lung cancer) in combination with other medicines.  It stops the growth of certain cancers.

When should Ifosfamide not be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, severe bone-marrow depression, pregnancy and breastfeeding.

What is the dosage of Ifosfamide?

IV- The recommended dose is 1.2 g/m per day for 5 consecutive days. Treatment is repeated every 3 weeks.

How should Ifosfamide be taken?

This medication is available in the form of injection administered by healthcare providers.

What are the warnings and precautions for Ifosfamide?

• Empty your bladder regularly. Get up at least once during the night to urinate.

It may reduce the number of blood cells that are needed for clotting. To prevent bleeding, avoid situations where bruising or injury may occur.

Drink adequate liquid during the treatment, otherwise it may lead to bladder irritation, especially important if you have had chemotherapy before.

Caution should be exercised in patients with history of liver or kidney disease, bone marrow problems, cancer that has spread to the bone marrow, infection, chickenpox, shingles, any allergy, who are taking other medications, during pregnancy and breastfeeding.

What are the side effects of Ifosfamide?

  Central Nervous System: Confusion, drowsiness, depression and agitation.
  Skin: Hair loss.
  Gastrointestinal: Nausea and vomiting.
  Miscellaneous: Eye inflammation, sore throat and shortness of breath.

What are the other precautions for Ifosfamide?

Monitor kidney functions, urine test, complete blood counts regularly.

What are the storage conditions for Ifosfamide?

Intravenous: Store at 20-25C.

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