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Gadoterate meglumine - Indications, Dosage, Side Effects and Precautions

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Information about Gadoterate meglumine

Generic Name : Gadoterate meglumine
Latest prescription information about Gadoterate meglumine. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
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Trade Names/Brand Names of Gadoterate meglumine

International- Dotatrem.
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Why is Gadoterate meglumine Prescribed? (Indications)

This medication is a gadolinium based contrast agent, prescribed for visualization of brain along with magnetic resonance imaging (MRI).  

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When should Gadoterate meglumine not be taken? (Contraindications)

Contraindicated in patients with hypersensitivity.

What is the dosage of Gadoterate meglumine?

IV- The recommended dose is 0.2 mL/kg, (0.1 mmol/kg) as bolus injection.

How should Gadoterate meglumine be taken?

It comes as a powder for injection (diluted with fluid) to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Gadoterate meglumine?

• Caution should be exercised in patients with history of acute kidney injury, impaired elimination of GBCAs, any allergy, who are taking other medications.

Patient with impaired elimination of GBCAs may experience with increased risk of Nephrogenic Systemic Fibrosis.

Monitor patients closely for need of emergency breathing support.

What are the side effects of Gadoterate meglumine?

  Most frequent: Nausea, headache, injection site pain, injection site coldness and burning sensation.
  Heart: Abnormal heart rhythm, fast or slow heart rate.
  Immune System: Hypersensitivity/anaphylactoid reactions including heart arrest, respiratory arrest, blue or purple coloration of the skin or mucous, throat swelling, asthma, eye inflammation, eyelid swelling, increased tears, increased sweating and hives.
  Central Nervous System: Coma, convulsion, fainting, lightheadedness, smell loss, tremor
  Musculoskeletal: Muscle contracture, muscle weakness.
  Gastrointestinal: Diarrhea, increased salivary secretion.
  General: Uneasiness and fever.
  Skin: Inflammation of a vein

What are the other precautions for Gadoterate meglumine?

Avoid excess dosage.

What are the storage conditions for Gadoterate meglumine?

Store it at controlled room temperature (25C).




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