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General Information on Ethinyl Estradiol and Levonorgestrel

Generic Name : Ethinyl Estradiol and Levonorgestrel

Pronunciation : ETH ih nill ess tra DYE all and lee voe nor JESS trell

Latest prescription information about Ethinyl Estradiol and Levonorgestrel. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.4 | Therapeutic Classification : Oral Contraceptives

Trade Names/Brand Names of Ethinyl Estradiol and Levonorgestrel

India- Choice Tab, Combee Tab, Combee-R Tab, Divacon Tab, Duoluton-L Tab, Ergest Tab, Ergest-Ld Pill, Locon Tab, Loette Tab, Oralcon-F Tab, Ovilow Film-Coated Tab, Ovipauz-L Film-Coated Tab, Ovral Tab, Ovral-G Tab, Ovral-L Tab, Trigestrel Tab, Triquilar Tab.
International- Jolessa and Seasonale.

Why is Ethinyl Estradiol and Levonorgestrel Prescribed? (Indications)

This combination medication contains estrogen and progestin, used as a highly effective oral contraceptive. In addition, it reduces the risk of ovarian and endometrial cancer, ovarian cysts and fibrocystic breast disease. It also helps to regularize cycles and reduce the incidence of anemia, premenstrual tension and pain during periods. It helps to improve endometriosis and pelvic inflammatory disease. 

When should Ethinyl Estradiol and Levonorgestrel not to be taken? (Contraindications)

Contraindicated in patients with undiagnosed vaginal bleeding, severe arterial disease, family history of high lipids; liver adenoma; inherited or acquired disorders of certain enzymes (porphyria); history of breast cancer; liver impairment; blood clot disorders; breast cancer; estrogen-dependent tumor; smoking, patients with diabetes complications; during pregnancy, migraine, high blood pressure, stroke ; gallstones; acute kidney failure (uremia) and a low platelet count, prior to major surgery; breast feeding during first 6 months after delivery.

What is the dosage of Ethinyl Estradiol and Levonorgestrel?

Adult: PO- Monophasic combined OC: As tab containing levonorgestrel 100-250 mcg and ethinyl estradiol 20-50 mcg: 1 tab once daily. Triphasic combined OC: Levonorgestrel 50-125 mcg + ethinyl estradiol 30-40 mcg: 1 tab once daily.

How should Ethinyl Estradiol and Levonorgestrel be taken?

It comes as a tablet to take by mouth once a day, with food or milk.

What are the warnings and precautions for Ethinyl Estradiol and Levonorgestrel?

Caution should be exercised in patients with history of sex-steroid dependent cancer, past ectopic pregnancy, indigestion, ovarian cysts, active liver disease, jaundice, heart or kidney impairment; diabetes, asthma, epilepsy, migraine, depression,lactation, conditions exacerbated by fluid retention; increased level of calcium in blood, gall bladder diseases, high lipid levels, patients at risk of venous blood clot, breast cancer, preexisting Fibroid Tumors of the Uterus and benign tumor of the liver.

Missed pills and interaction with other drugs may require additional contraceptive precautions.

What are the side effects of Ethinyl Estradiol and Levonorgestrel?

  Genitourinary: Menstrual irregularities, spotting, inflammation of vagina, breast cancer, tenderness, pain, enlargement, secretion, infertility after discontinuation of treatment.
  Central Nervous System: Headache, dizziness, depression, changes in libido.
  Gastrointestinal: Disturbance of appetite, nausea and vomiting, abdominal pain, cramps, and bloating, inflammation of pancreas.
  Skin: Hair loss, local skin reactions, acne, severe allergic reactions, rash, darkening of skin over face.
  Liver: Liver impairment, jaundice, gallstone formation.
  Heart: High blood pressure.
  Miscellaneous: Loss/Gain in weight.
  Potentially Fatal: Liver tumors, increased risk of blood clot, increased chances of breast or cervical cancers in patients already at risk for these cancers.

What are the other precautions for Ethinyl Estradiol and Levonorgestrel?

Take properly s directed by your physician, without missing your dosage.

What are the storage conditions for Ethinyl Estradiol and Levonorgestrel?

Store it at room temperature and in airtight container.


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
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Nikita.bharati, Nepal

My mother is suffering from Urinary Track Infection, she suffers from burning vagina. Doctor had initially prescribed her Ciprofloxacin, but it didn't worked. After Urine Culture report, she took Nitrofurantoin for 10 days. Now, she has stopped taking any medicines. She is not recovered yet. She has been suffering from this since 5-6 months. Recently, we went to visit the doctor and she has prescribed this medicines for 3 months. How will this reduce the burning sensation in genitals?

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