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Ansuvimab - Indications, Dosage, Side Effects and Precautions

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Information about Ansuvimab

Generic Name : Ansuvimab
Pronunciation : an SOO vi mab
Latest prescription information about Ansuvimab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
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Trade Names/Brand Names of Ansuvimab

Ebanga
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Overview of Ansuvimab

Ansuvimab is indicated for the treatment of infection caused by Zaire ebolavirus in adults and kids, including newborns of mothers who are RT-PCR positive for Zaire ebolavirus infection.

Why is Ansuvimab Prescribed? (Indications)

Ansuvimab is a monoclonal antibody prescribed for treating Zaire ebolavirus infection. This virus can change over time and there is high chance of emergence of resistance. 

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When should Ansuvimab not be taken? (Contraindications)

Allergic to Ansuvimab
Pregnancy
Children aged below 18 years
Adults aged above 65 years

What is the dosage of Ansuvimab?

It is available as injection: 400 mg lyophilized powder in a single-dose vial for reconstitution and further dilution. Dose should be calculated based on the patients actual weight in kg.

How should Ansuvimab be taken?

The recommended dose is 50 mg/kg reconstituted. It is administered as a single intravenous infusion over 60 minutes.
It should be reconstituted with sterile water for injection, then further diluted in 0.9% Sodium Chloride injection. Before reconstitution, allow the vial to reach ambient temperature (15C to 27C [59F to 81F]) for 20 minutes.
The diluted IV solution can be infused via a central line or peripheral catheter. It should not be given as an IV push or bolus.

What are the side effects of Ansuvimab?

General: Fever, chills
Cardiovascular:-ore heart rate Rapid heartbeat (Tachycardia), Low blood pressure
Gastrointestinal: Diarrhea, Vomiting
Respiratory system: Increased respiratory rate

What are the other precautions for Ansuvimab?

Ansuvimab may cause allergic reactions including infusion-related events, which may be acute, life-threatening reactions during and after the infusion. In case of severe or life-threatening hypersensitivity reactions, discontinue the administration immediately and seek appropriate emergency care.
Patients infected with Zaire ebolavirus should not breastfed.

What are the Drug Interactions of Ansuvimab?

Do not take Ansuvimab with: Live vaccines

What are the storage conditions for Ansuvimab?

Store Ansuvimab injection in ambient temperature (15C to 27) or in the refrigerator at 2 to 8oC It should be protected from light

Last Updated : 7/5/2021



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