This medication is an antineoplastic alkylating agent, prescribed for certain types of cancer such as ovarian cancer. It slows the cancer cells growth.

Contraindicated in patients with preexisting severe bone marrow depression, and hypersensitivity.

Adult- PO- It may be administered either for 14 or 21 consecutive days in a 28 day cycle at a dose of 260 mg/m²/day.

It comes as a capsule to take by mouth, with food and at bedtime.

• Caution should be exercised in patients with history of bone marrow cancer, bone marrow depression, decrease in white blood cells, liver problem, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

•   Central Nervous System : Mood disorders, loss of consciousness, incoordination, dizziness and fainting.
•   Gastrointestinal : Nausea and vomiting.
•   Blood : Bone marrow depression.
•   Genitourinary : BUN- Blood urea nitrogen.

Avoid excess dosage.

Store it at room temperature (25°C).