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Alpha One-proteinase inhibitor - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Alpha One-proteinase inhibitor

Generic Name : Alpha One-proteinase inhibitor
Pronunciation : AL-fa 1 PROE-teen-ase
Latest prescription information about Alpha One-proteinase inhibitor. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y57.9 | Therapeutic Classification : Blood Modifier Agents
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Trade Names/Brand Names of Alpha One-proteinase inhibitor

International- Zemaira.
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Why is Alpha One-proteinase inhibitor Prescribed? (Indications)

Alpha One-proteinase inhibitor is prescribed to treat alpha -1 antitrypsin deficiency, a genetic disorder which may lead to lung damage or emphysema (damage to the air spaces in the lungs).

Alpha-1 antitrypsin is a protein which is used to prevent the breakdown of tissues in lungs.  

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When should Alpha One-proteinase inhibitor not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Alpha One-proteinase inhibitor?

IV- The recommended dose is 60-mg/kg body weight administered once weekly.

How should Alpha One-proteinase inhibitor be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Alpha One-proteinase inhibitor?

• Caution should be exercised in patients with history of heart or circulatory problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Alpha One-proteinase inhibitor?

   Most Common : Weakness, injection site pain, dizziness, headache, tingling, and itching.
   Miscellaneous : Upper respiratory tract infection, inflammation sinus, injection site bleeding, sore throat, fever, runny nose, asthma, chest pain, increased cough, rash, and infection.

What are the other precautions for Alpha One-proteinase inhibitor?

Avoid excess dosage.

What are the storage conditions for Alpha One-proteinase inhibitor?

Store it in room temperature (25C).

Last Updated : Jul 2018



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