Agalsidase is prescribed for treating patients with Fabry disease; a rare genetic disorder occurs due to a deficiency of alpha-galactosidase-A (an enzyme responsible for breaking down fat). Agalsidase provides the enzyme alpha-galactosidase A to the body.
The recommended dosage is 1.0 mg/kg body weight infused every 2 weeks as an IV infusion.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of heart or lung problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• Most Common :
Chills, fever, feeling hot or cold, difficulty in breathing, nausea, swelling of the face, mouth, and throat, flushing, headache, vomiting, tingling, fatigue, itching, pain in extremity, high blood pressure, chest pain, throat tightness, abdominal pain, dizziness, fast heart rate, nasal congestion, diarrhea, muscle pain, back pain, pallor, slow heart rate, hives, low blood pressure, face swelling, rash, and drowsiness.
• Infections : Upper respiratory tract infection and fungal infection.
• Central Nervous System : Anxiety and depression.
• Respiratory : Cough, difficulty in breathing and wheezing.
Avoid excess dosage.
Store it in refrigerator (2°-8°C). Do not freeze it.
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