Information about Agalsidase

Generic Name : Agalsidase
Up-to-date prescription details regarding Agalsidase are provided here.

Pronunciation : aye-GAL-sih-dace

Learn the correct pronunciation of the Agalsidase, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Therapeutic Classification : Endocrine and Metabolic Agents

Trade Names/Brand Names of Agalsidase

India :

Galazyme, Gastica plus, Leno.

International :

Fabrazyme, Replagal

Why is Agalsidase Prescribed? (Indications)

Agalsidase is prescribed for treating patients with Fabry disease; a rare genetic disorder occurs due to a deficiency of alpha-galactosidase-A (an enzyme responsible for breaking down fat). Agalsidase provides the enzyme alpha-galactosidase A to the body.

When should Agalsidase not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Agalsidase?

The recommended dosage is 1.0 mg/kg body weight infused every 2 weeks as an IV infusion.

How should Agalsidase be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Agalsidase?

• Caution should be exercised in patients with history of heart or lung problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Agalsidase?

Most Common - Chills, fever, feeling hot or cold, difficulty in breathing, nausea, swelling of the face, mouth, and throat, flushing, headache, vomiting, tingling, fatigue, itching, pain in extremity, high blood pressure, chest pain, throat tightness, abdominal pain, dizziness, fast heart rate, nasal congestion, diarrhea, muscle pain, back pain, pallor, slow heart rate, hives, low blood pressure, face swelling, rash, and drowsiness.
Infections - Upper respiratory tract infection and fungal infection.
Central Nervous System - Anxiety and depression.
Respiratory - Cough, difficulty in breathing and wheezing.