Ambulatory Blood Pressure Monitoring in Kidney Disease Patients

The potential benefits of blood pressure monitoring outside of doctors’ offices for patients with kidney disease have been examined by two studies published in CIASN. This type of monitoring can provide more information than blood pressure //measurements taken only in clinics. In an analysis of 561 African Americans with and without chronic kidney disease who underwent ambulatory blood pressure monitoring, Paul Muntner, MD, Stanford Mwasongwe, MPH (University of Alabama at Birmingham), and their colleagues found that having kidney disease was associated with uncontrolled blood pressure measured in the clinic and outside of the clinic.

Also, among participants with kidney disease, uncontrolled ambulatory blood pressure was associated with a higher prevalence of left ventricular hypertrophy, a marker of cardiovascular disease.

In another study that followed 1,502 adults with chronic kidney disease for 4 years, Lama Ghazi, MD (University of Minnesota) and her colleagues found that ambulatory blood pressure patterns were not linked with cognitive impairment or frailty.

“However, among participants older than 60 years, those who demonstrated at least a 20% drop in average systolic blood pressure from day to night—called extreme dippers—had a higher risk of developing cognitive impairment,” said Dr. Ghazi. Also, participants with masked hypertension (normal clinic-measured blood pressure but elevated ambulatory blood pressure) had worse physical functioning than participants with hypertension controlled with medication.

Dr. Ghazi noted that future research should assess links between ambulatory blood pressure and physical and cognitive function over a longer follow-up period.

Source-Newswise