How it should be taken
It comes as a capsule and tablet to take by mouth, with or without food.
Dosage & When it is to be taken
Dosing of children and adolescents up to 70 kg body weight
Initial: The recommended dose is 0.5 mg/kg and increased after a minimum of 3 days to a target total daily dose of approximately 1.2 mg/kg administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening. The total daily dose in children and adolescents should not exceed 1.4 mg/kg or 100 mg.
Dosing of children and adolescents over 70 kg body weight and adults
Initial: The recommended dose is 40 mg and increased after a minimum of 3 days to a target total daily dose of approximately 80 mg administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening.
When it is not to be taken (Contraindications)
Contraindicated in patients with narrow-angle glaucoma, severe cardiovascular disease
, co-administered with MAOIs or within 14 days of treatment with MAOIs and hypersensitivity.
Why it is prescribed (Indications)
This medication is a selective norepinephrine reuptake inhibitor (SNRI), prescribed for Attention deficit hyperactivity disorder (ADHD).
It increases the level of norepinephrine in the brain, which is needed to control behavior.
Category C :
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution should be exercised in patients with history of depression or bipolar disorder, suicidal thoughts, high or low blood pressure, seizures, liver diseases, heart problems, stroke, blood or bleeding problems, seizures, trouble urinating, Raynaud syndrome, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, drowsiness, lightheadedness or fainting, do not drive a car or operate machinery and sit up or stand slowly from bed while taking this medication.
Avoid alcohol consumption.
Monitor blood pressure and heart rate regularly while taking this medication.
Store it at controlled room temperature (25°C).