Medindia » Medication Manual » Roxatidine

Roxatidine

Latest prescription information about Roxatidine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Roxatidine
Therapeutic Classification : Antiulcers
ICD Code : Y53.0
Trade Name(s): 
India- Rotane SR, Zorpex SR.
International- Zorprex.
Why it is prescribed (Indications) : 
This medication is a special H2-receptor antagonist, prescribed for reflux esophagitis, benign gastric ulcer, duodenal ulcer and prophylaxis of recurrent ulcers.  
When it is not to be taken (Contraindications): 
Contraindicated in patients with absence of urination, gastric malignancy and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- The recommended dose is 150mg/day.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney or liver impairment, during pregnancy and breastfeeding.
Side Effects : 
Skin- Rash.
Gastrointestinal- Constipation, diarrhea, nausea and gastrointestinal disturbances.
Central Nervous System- Weakness, headache, dizziness, restlessness and drowsiness.
Heart- Fast heart rate and chest pain.
Liver- Increased liver enzyme activity.
Miscellaneous- Visual disturbances, impotence and increased level of lipid in blood.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it at room temperature and in an airtight container. Keep away from children.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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