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Generic Name : Proguanil
Pronunciation : proe-GWAHN-il
Trade Name(s):
India- Laveran, Progunal Tab. International- Malarone- Atovaquone +Proguanil. This medication is an antiprotozoal and antimalarial, prescribed for prevention of malaria, treatment of malaria. It prevents the development of malaria parasites. When it is not to be taken (Contraindications):
When it is to be taken : Adult: PO- Malaria prophylaxis- 200 mg/day with chloroquine or 100 mg/day with atovaquone. Start 1 week before exposure to malaria or 1-2 days prior to travel. Continue throughout exposure and for at least 4 week (or 1 week if given with atovaquone) after leaving a malaria-infested area. How it should be taken : It comes as a tablet to take by mouth (orally), with food. Special Instruction : *It may not work as well if you have severe or persistent vomiting or diarrhea. *It may make you drowsy. Do not drive a car or operate machinery while taking this medication. *Caution needed for patients with history of kidney disease, pregnancy, breast feeding, elderly, and children. * If you experience with vomiting within one hour after taking this medication, take another dose. Side Effects : Most Common in adult- Abdominal pain, nausea, vomiting, headache, diarrhea, weakness, loss of appetite, and dizziness. Children- Vomiting, and itching. Kidney- Blood in urine. Blood - Abnormally decrease in white blood cells, and rarely anemia. Decrease in all types of blood cells. Allergic reactions- Allergic reactions including rapid swelling, hives, rare cases of life-threatening allergies, and inflammation of blood vessels. Central Nervous System - Rarely seizures and hallucinations. Gastrointestinal - Mouth ulcer. Liver- Elevated liver function tests and rare cases of liver inflammation. Skin - Photosensitivity, rash, and rare cases of erythema multiforme and Stevens-Johnson syndrome. *Avoid abrupt withdrawal. Storage Conditions : Store it in an airtight container; keep away from children and pets. |
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