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Generic Name : Mexiletine
Pronunciation : mex-IL-e-teen
Therapeutic Classification : antiarrhythmics
Trade Name(s):
International- Mexitil Cap, Mexitil Inj. This medication is used to treat irregular heart rhythms (arrhythmias) and maintain a normal heart rate. It is an antiarrhythmic. It blocks certain electrical signals in the heart to stabilize the heart rhythm. When it is not to be taken (Contraindications):
When it is to be taken : IV- The recommended dose is 100-200mg, over 10 minutes (1mg/min) infusion. PO- The recommended dose is 150-200mg, three times a day with meals. How it should be taken : It comes as a capsule to take by mouth with food, either twice or thrice depending upon patient’s condition. It is also administered as an infusion at the rate of 1 mg/min. Special Instruction : *Caution needed for patients with history of acute MI, sinus node dysfunction, conduction defects, slow heart rate, low blood pressure, heart failure, liver impairment, pregnancy. *Monitor ECG and BP. *Correct electrolyte imbalance prior to and during therapy. *It may cause dizziness, avoid driving a car or operate machines, or other unsafe tasks. Side Effects : Heart- Palpitations, chest pain, increased heart rhythm and heart failure. Central Nervous System- Dizziness, lightheadedness, tremor, nervousness, coordination difficulties, headache, changes in sleep habits, weakness, tingling, numbness, fatigue, speech difficulties, confusion, depression and drowsiness. Liver- Increased liver enzymes and liver damage. Skin- Rash. Eye and ENT- Blurred vision, visual disturbances, ringing in ears, and uncontrolled movement of the eyes. Gastrointestinal- Nausea, vomiting, heartburn, diarrhea, constipation, changes in appetite, dry mouth, abdominal pain, cramps, or discomfort. Blood- Decrease in white blood cells and platelets. Musculoskeletal- Muscle pain. Respiratory- Difficulty in breathing. Miscellaneous- Non-specific swelling, fever and hypersensitivity. * Avoid excess dosage. Storage Conditions : Store at 25°C. Store it in an airtight container and keep away from children. |
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