Albendazole - Drug Information

Generic Name : Albendazole | Pronunciation : al-BEN-da-zole

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Latest prescription information about Albendazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.4 | Therapeutic Classification : Antihelmintics
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Trade Name(s): 
India :  More...

International : Albenza, Eskazole, Zentel, Andazol and Alworm

Why it is prescribed (Indications) : 
This medication is an anthelmintic, prescribed for tapeworm infections, hydatid cyst disease, cysticercosis or neurocysticercosis, capillariasis, cutaneous larva migrans, giardiasis, microsporidiosis including Septata intestinalis infection, intestinal parasites in immigrants, strongyloidiasis, trichinosis, trichostrongyliasis. It works by killing sensitive parasites.

When it is not to be taken (Contraindications): 
Contraindicated in pregnant and breastfeeding women, neonates, patients with known hypersensitivity, and liver impairment.

Pregnancy Category :

A B C D X

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Dosage & When it is to be taken : 
Dosing of ALBENZA (albendazole) will vary, depending upon which of the following parasitic infections is being treated.
Hydatid cyst disease: PO- Adults >= 60 kg: 400 mg twice daily with meals for 28 days followed by a 14-day drug-free period. Repeat for 2 more cycles. For inoperable hydatid cysts, up to 5 cycles may be given.
Adults < 60 kg: 15 mg/kg/day (not to exceed 800 mg/day) given in two divided doses for 28 days followed by a 14-day drug-free period. Repeat as above. Children >= 6 years: 15 mg/kg/day given in two divided doses for 28 days, followed by a 14-day drug-free period. Repeat as above.
Cysticercosis or neurocysticercosis (larval form of T. solium): PO- Adults >= 60 kg: 400 mg twice daily for 8 - 30 days. Treatment may be repeated as necessary. Adults < 60 kg: 15 mg/kg/day given in two divided doses for 8 - 30 days. Maximum dosage 800 mg/day. Treatment may be repeated as necessary.
Children >= 6 years: 15 mg/kg/day given in two divided doses for for 8 - 30 days. Maximum dosage 800 mg/day. Treatment may be repeated as necessary.
Capillariasis: PO- Adults and Children >= 2 years: 200 mg twice daily for 10 days.
Cutaneous larva migrans: PO- Adults: 400mg once daily for 3 days.
Children: 5 mg/kg/day for 3 days.
Giardiasis: PO- Adults: 400 mg once daily for 3 days.
Microsporidiosis including Septata intestinalis infection: PO- Adults: 400 mg twice daily to 1600 mg twice daily has been used. Average dosage 800 mg twice daily. May take up to 2 months to see effect.
Intestinal parasites in immigrants: PO- Adults: 400 mg once daily for 5 days.
Strongyloidiasis or taeniasis † (tapeworm infection): PO- Adults and Children >= 2 years: 400 mg once daily for 3 days. May repeat course in 3 weeks. Children < 2 years: 200 mg once daily for 3 days. May repeat course in 3 weeks.
Trichinosis: PO- Adults: 400 mg twice daily for 15 days.
Trichostrongyliasis: PO- Adults: 400 mg as a single dose.

How it should be taken : 
It comes in a tablet form to take by mouth (orally). Should be taken with food.

Warnings and Precautions : Monitor blood counts and liver function.
Patients being treated for neurocysticercosis should receive appropriate steroid and anticonvulsant therapy as required.
It is important to take iron every day while you are being treated for hookworm infection because it causes anemia.
Administer within 7 days of start of normal menstruation in women of childbearing age.
Adequate non-hormonal contraceptive measures must be taken during and for 1 month after therapy.
Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease.
It may cause bone marrow depression.
It may cause dizziness. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
In young children, the tablets should be crushed or chewed and swallowed with glass of water.

Side Effects : Central Nervous System- Headache, seizures, confusion, raised intracranial pressure, dizziness/vertigo, signs that meningeal sings.
Skin- Reversible hair loss, infection, hypersensitivity including rash and hives, allergic reactions.
Gastrointestinal- Abdominal pain, nausea/vomiting.
Genitourinary- Acute kidney failure, dark urine.
Liver- Abnormal Liver Function Tests, inflammation of liver
Blood- Decrease in the number of white blood cells, thrombocytes, hemoglobin.
Miscellaneous- Fever.

Other Precautions : Do not change the dose, without your Doctor's advice.

Storage Conditions : Store in room temperature in an airtight container and keep away from excess heat, moisture and children.

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pravy
hi sir good morning, i want to know that my mother is suffering from hydatid cyst in liver of heterogenous size of 8.5*6.5 and on abdominal wall the center close to periumblical region size ranges 4.5*3.7,2.8*3.2,,,we got dis after sonography,doctor said ct scanning laproscopic operation ,and give albendazole treatment for 30 days .Is tab. does tablet also work as operation therapy???
SIR I M WAITING FOR YOUR GOOD REPLY??

pravy  Saturday, August 25, 2012
MEJAGAN
I met with an accident in Oct. 2005 no paid or bleeding. No fracture also. Hence no precaution taken. After 3 days of accident my right leg swelled heavily. Then admitted in to hospital & 3 times operated at the infected area. Still the leg was little big. After 6 months a viral fever affected me & the legs became big. Again 2 operations done. Now the R-leg is 3 times than L-leg. No pain or disable. Please suggest a midicine. JAGAN, Mumbai
MEJAGAN  Wednesday, April 25, 2012
ifeanyi
more drug names should be listed for filariasis almost all the one listed is not in Nigeria Country.
ifeanyi  Monday, December 20, 2010
SKS997
Every adult living in North Bihar must take a course of Albendazole. 1 tabs daily for 3 days and repeat the course after 3 weeks.
Regards,
Sudhir K Sinha.
SKS997  Thursday, November 11, 2010
nihalanigovind
can it be used as normal deworming drug? if yes, indicate dose
nihalanigovind  Monday, September 20, 2010

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