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Adenosine

Latest prescription information about Adenosine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Adenosine
Pronunciation : a-DEN-oh-seen
Therapeutic Classification : Antiarrhythmics
ICD Code : Y52.2
Trade Name(s): 
India: Adenocor, Adenoject,Adenoz, Cadsine,Carnosin,Tachyban.
International: Adenocard.
Why it is prescribed (Indications) : This medication is an antiarrhythmic agent, prescribed for irregular heart beat. It slows the electrical conduction in the heart.
When it is not to be taken (Contraindications): Contraindicated in patients with second-or third-degree AV block, slow heartbeat, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Adult- IV- Initial dose: 6 mg given as a rapid intravenous bolus (administered over a 1-2 second period). Repeat Administration: If first dose does not work, 12 mg should be given as a rapid intravenous bolus. This 12 mg dose may be repeated a second time if required.
Child- Initial dose: Give 0.05 to 0.1 mg/kg as a rapid IV bolus. It may be increased upto 0.05 to 0.1 mg/kg if needed.
How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of lung or breathing problems, any allergy, who are taking other medications, elderly, during pregnancy and breast-feeding.
* It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid drinking large amount of caffeinated beverages.
Side Effects : 
Heart - Facial flushing, headache, sweating, palpitations, chest pain and low blood pressure.
Respiratory - Shortness of breath, chest pressure, fast breathing and head pressure.
Central Nervous System - Lightheadedness, dizziness, tingling in arms, numbness, apprehension, blurred vision, burning sensation, heaviness in arms, neck and back pain.
Gastrointestinal - Nausea, metallic taste, tightness in throat and pressure in groin.
Other Precautions : 
* Monitor electrocardiogram (ECG) regularly while taking this medication.
Storage Conditions : 
Store it at controlled room temperature (15º-30ºC), and in an airtight container.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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