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General Information on Adefovir Dipivoxil

Generic Name : Adefovir Dipivoxil

Pronunciation : a-DEF-oh-vir dye-piv-OX-il

Latest prescription information about Adefovir Dipivoxil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.5 | Therapeutic Classification : Antivirals

Trade Names/Brand Names of Adefovir Dipivoxil

India : 

International : 

Hepsera

Why is Adefovir Dipivoxil Prescribed? (Indications)

This medication is a reverse transcriptase inhibitor (ntRTI), prescribed for hepatitis B, in patients 12 years of age and older with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease. and herpes simplex virus infection. It slows the growth of HBV by blocking reverse transcriptase, an enzyme that is helpful for viral reproduction.  It slows the growth of HBV by blocking reverse transcriptase, an enzyme that is helpful for viral reproduction.

When should Adefovir Dipivoxil not to be taken? (Contraindications)

Contraindicated in patients who are taking tenofovir, liver enlargement and hypersensitivity.

What is the dosage of Adefovir Dipivoxil?

Adult- PO -The recommended dose is 10mg/day.

How should Adefovir Dipivoxil be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Adefovir Dipivoxil?

Caution should be exercised in patients with history of kidney, liver diseases, abnormal liver function tests, liver transplant, HIV infection, obesity, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
It should not be used in children less than 12 years old.
Monitor kidney and liver functions regularly while taking this medication.
If condition worsens stop the medication immediately.
Should not be used concurrently with tenofovir disoproxil fumarate or tenofovir disoproxil fumarate-containing products.

What are the side effects of Adefovir Dipivoxil?

   Most Common : Weakness, headache, abdominal pain, diarrhea, nausea, indigestion, flatulence, increased creatinine, and decrease in blood phosphate level.
   Gastrointestinal : Inflammation of pancreas.
   Muscuskeletal : Muscle pain and softening of bones.
   Genitourinary : Kidney failure and Fanconi syndrome.

What are the other precautions for Adefovir Dipivoxil?

It does not stop the spread of HBV to others; avoid sexual contact, sharing of needles and injection supplies.

What are the storage conditions of Adefovir Dipivoxil?

Store it in room temperature (25C), and in an airtight container.

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