Why it is prescribed :
Abacavir is an antiviral drug that is effective against the HIV-1 virus. It acts on an enzyme of the virus called reverse transcriptase, which plays an important role in its multiplication. Though abacavir reduces viral load and may slow the progression of the disease, it does not cure the HIV infection.
When it is not to be taken (Contraindications):
Moderate to severe liver disease
Previous allergic reaction to abacavir
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Treatment of HIV-1/AIDS along with other medications. Dose in adults is 600 mg daily, as a single dose or divided into two doses.
How it should be taken :
It comes as a tablet to take with or without food. It is also available in combination with other anti-HIV drugs.
Warnings and Precautions :
Caution is advised when used in patients with history of depression or at risk for heart disease
Avoid use with alcohol.
Take along with other anti-HIV drugs and not alone, to prevent resistance.
Continue other precautions to prevent spread of HIV infection.
Storage Conditions :
Store at room temperature (20° to 25°C).