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Malaria treatment

Last Updated on May 21, 2020
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Treatment to Malarial infections

  • Each form of malaria requires different type of treatment.
  • The drugs used for treatment of malaria is called anti-malarial drugs
  • The common anti-malarial drugs are:
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- Cinchona alkaloids

- Cinchona febriguge

- Tota quina

Quinine derivatives /Quinine sulphate:

  • Destroys the asexual forms of Plasmodium in three days.
  • Used in the treatment of cerebral malaria, it clears the clogs in the brain capillaries caused by Plasmodium falciparum.
  • Not toxic in recommended dosage but excessive dosage may cause temporary deafness.
  • Pregnant women should not be given quinine derivatives.
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Acridine derivatives/Mepacrine and Quinacrine:

  • Destroys the asexual forms of plasmodium after the third or fourth day.
  • Toxic effects are temporary yellow coloration of skin, face, eyes and urine.

Biguanie/Paludrine:

  • Destroys the tissue forms and can be used as a prophylactic drug.

- Prophylactic dosage 300 mgs once a week

- For treatment 300 mgs daily for 5 to 10 days

  • Side effects - nausea and vomiting may occur.
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4-Aminoquinolines / Avloclor, Chloroquine, Resochin, Nivaquin, Arolon and Camaquin :

  • Powerful schizonticidal drug acts on the asexual forms of plasmodium.
  • Side effects - dizziness and sleeplessness occurs on excessive dosage.

8-Aminoquinolines/Primaquine

  • Powerful gametocidal drug kills the the gametocytes.
  • Toxic side effects- Cyanosis and black urine can occur and treatment as to be stopped immediately

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Comments

moses odradria

this was wonderfully done

camaldina

Thanks for write-pus. Its very informative. You only talked about the treatment of malaria, but what about the treatment/avoidance of the Malaria Relapses, which is very important?

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