Treatment to Malarial infections

  • Each form of malaria requires different type of treatment.
  • The drugs used for treatment of malaria is called anti-malarial drugs
  • The common anti-malarial drugs are:

- Cinchona alkaloids

- Cinchona febriguge

- Tota quina

Quinine derivatives /Quinine sulphate:

  • Destroys the asexual forms of Plasmodium in three days.
  • Used in the treatment of cerebral malaria, it clears the clogs in the brain capillaries caused by Plasmodium falciparum.
  • Not toxic in recommended dosage but excessive dosage may cause temporary deafness.
  • Pregnant women should not be given quinine derivatives.

Acridine derivatives/Mepacrine and Quinacrine:

  • Destroys the asexual forms of plasmodium after the third or fourth day.
  • Toxic effects are temporary yellow coloration of skin, face, eyes and urine.

Biguanie/Paludrine:

  • Destroys the tissue forms and can be used as a prophylactic drug.

- Prophylactic dosage 300 mgs once a week

- For treatment 300 mgs daily for 5 to 10 days

  • Side effects - nausea and vomiting may occur.

4-Aminoquinolines / Avloclor, Chloroquine, Resochin, Nivaquin, Arolon and Camaquin :

  • Powerful schizonticidal drug acts on the asexual forms of plasmodium.
  • Side effects - dizziness and sleeplessness occurs on excessive dosage.

8-Aminoquinolines/Primaquine

  • Powerful gametocidal drug kills the the gametocytes.
  • Toxic side effects- Cyanosis and black urine can occur and treatment as to be stopped immediately

Comments

moses odradria Thursday, January 5, 2012

this was wonderfully done

camaldina Sunday, February 6, 2011

Thanks for write-pus. Its very informative. You only talked about the treatment of malaria, but what about the treatment/avoidance of the Malaria Relapses, which is very important?

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