DNA Damage and Ageing
What is the basis of ageing and age-related diseases? Various studies point to the accumulation of damage on the DNA, also called mutations, to be the causative factor.
Every living cell harbors mitochondria, other wise known as the cell’s ‘power house’ that recruits oxygen to produce energy. The by-products of this process are the oxidants that damage the DNA and other cell components. However the cells are not without their own soldiers. The ‘surveillance’ genes are geared into action to defend the cells against the damaging oxidants and to repair the existing damage.