Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial
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Stem Cell Therapy’s Safety and Promising Benefits
"This study documents the safety and potential benefit of stem cells and regenerative medicine," said Mohamad Bydon, a neurosurgeon at Mayo Clinic. The study, appearing in the journal Nature Communications, included 10 adults. Of these, seven demonstrated improvements like “increased sensation when tested with pinprick and light touch, increased strength in muscle motor groups, and recovery of voluntary anal contraction, which aids in bowel function.”
Spinal Cord Injury
Spinal cord injury is an injury to the spinal cord that results in temporary or permanent changes in its function.
Spinal cord injury is an injury to the spinal cord that results in temporary or permanent changes in its function.
‘Stem cells sourced from a patient's adipose tissue offer a safe avenue and hold promise in enhancing sensation and mobility for individuals enduring spinalcordinjuries and paralysis. #stemcells #spinalcordinjuries #medindia
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While the remaining three patients showed no improvement, it did not get worse, the trial showed. No serious adverse events were recorded after the treatment, and the most commonly reported side effects were headache and musculoskeletal pain that resolved with over-the-counter treatment. Even as the spinal cord has limited ability to repair its cells or make new ones, “even a mild improvement can make a significant difference in that patient’s quality of life," Dr. Bydon said. The World Health Organization (WHO) estimates that between 250,000 and 500,000 people worldwide suffer a spinal cord injury each year. However, options to improve the condition are extremely limited.
"For years, treatment of spinal cord injury has been limited to supportive care, more specifically stabilization surgery and physical therapy," Dr. Bydon said. "Spinal cord injury is a complex condition. Future research may show whether stem cells in combination with other therapies could be part of a new paradigm of treatment to improve outcomes for patients," he added.
Test Your Knowledge on Spinal Cord Injury
Often a sudden traumatic injury or a non-traumatic condition results in a fracture or dislocation of vertebrae which can further cause spinal cord damage. Vertebral injuries may result in a partial or complete transaction of the spinal cord which ...
Often a sudden traumatic injury or a non-traumatic condition results in a fracture or dislocation of vertebrae which can further cause spinal cord damage. Vertebral injuries may result in a partial or complete transaction of the spinal cord which ...
- Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial - (https://www.nature.com/articles/s41467-024-46259-y)
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Gene Therapy Sparks Spinal Cord Regeneration
Team at NeuroRestore introduces a groundbreaking gene therapy that has effectively promoted nerve regrowth and reconnection, post spinal cord injury.
Team at NeuroRestore introduces a groundbreaking gene therapy that has effectively promoted nerve regrowth and reconnection, post spinal cord injury.
Softening Stem Cells Enhances Hair Growth Potential
The scientists discovered that when the stem cells in the hair follicle are made softer, they have a higher chance of growing hair.
The scientists discovered that when the stem cells in the hair follicle are made softer, they have a higher chance of growing hair.
