"My body's tired. I've put it through too much, abused it and my body is knackered," Contactmusic quoted her, as saying.
She said that she was very much content with the way she looks at her age.
"I am content with how I look at my age and I'm really scared of ending up looking like those people whose faces are ironed and foreheads don't move," she said.
Osbourne, 54, confessed that she had spent over 120,000 pounds on nip-and-tuck procedures.
But the rock mum now rules out the options of getting any surgeries.
"I regret having my breasts done because I'm never happy with them. But the most painful was having my legs lifted.
"They literally cut all the way around the top of your thigh, pull up the skin like a stocking, then cut the excess away and sew it back on. When I came round I thought they'd sewn my legs together the swelling was so bad.
"So right now, I've really, really had it with surgery," she said.