A part of the Papez circuit, the fornix, transfers information of episodic memory between the medial temporal lobe and the medial diencephalon.
It is difficult to precisely assess the fornix due to its long, thin appearance and its location within the brain. In addition, discrimination of the whole fornix from adjacent neural structure using conventional brain CT or MRI is impossible. By contrast, diffusion tensor tractography (DTT) has enabled three-dimensional visualization of the fornix, and many studies have reported on fornix injury using DTT.
Dr. Sung Ho Jang and co-workers from College of Medicine, Yeungnam University, Republic of Korea using DTT, report on a male patient, 33 years old, who showed selective verbal memory impairment due to left fornical crus injury following intraventricular hemorrhage (IVH). The patient showed impairment in both visual and verbal memory at 1 month after onset; in contrast, at 4 months after onset, the patient showed selective verbal memory impairment with marked improvement of visual memory.