About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Reveal How Women With Lupus can Boost Their Chances of Healthy Pregnancies

by Rajashri on October 29, 2008 at 2:50 PM
Font : A-A+

Scientists Reveal How Women With Lupus can Boost Their Chances of Healthy Pregnancies

The mechanism behind how women suffering from systemic lupus erythematosus (SLE), an autoimmune disease, can have successful pregnancies, has been uncovered by rheumatologists at Hospital for Special Surgery in New York.

Earlier, women with SLE were advised not to have children, and in case they did conceive a child, they were advised to have therapeutic abortions to prevent severe flares of their lupus.

Advertisement

Now, the new research provides information that may yield insights that support a reversal of that thinking.

Titled, the PROMISSE (Predictors of pRegnancy Outcome: bioMarkers In antiphospholipid antibody Syndrome and Systemic lupus Erythematosus) Study, the multi-center research is led by Jane Salmon, M.D., attending physician at Hospital for Special Surgery.
Advertisement

Salmon will present two research projects based on data gathered from the PROMISSE Study.

The researchers identified factors that help a woman and her doctor plan for a healthy pregnancy.

Lupus patients usually experience a disease "flare" quite late, when symptoms such as a red rash across the nose and cheeks, painful or swollen joints, swollen legs or extreme fatigue appear suddenly.

For the first presentation, aimed at finding if problems during pregnancy can be correlated to the severity, the researchers followed 198 pregnant patients with lupus.

They found that women who conceived while their disease was stable or only mildly active had relatively infrequent flares during their pregnancies and delivered healthy babies, regardless if past disease severity or past kidney disease

The findings inform women with lupus on how to plan when to conceive to have a low risk pregnancy.

Patients with Lupus, as well as other patients with the antiphospholipid syndrome, produce special types of proteins called antiphospholipid antibodies that can attack their own tissues and cause pregnancy complications.

The second study showed that the presence of a specific subset of these autoantibodies is linked with poor pregnancy outcomes.

In fact, they found that women having an autoantibody called lupus anticoagulant were more prone to have complications such as miscarriage or preeclampsia during pregnancy.

With the help of these findings, it is possible to identify patients at high risk for complications just by a blood test to determine if they are positive or negative for the lupus anticoagulant autoantibody.

Though it is possible for women with lupus or the antiphospholipid syndrome who are positive for this protein to have successful pregnancies, their doctors should monitor them more closely for early signs of pregnancy complications.

The two studies will be presented at this year's American College of Rheumatology meeting in San Francisco.

Source: ANI
RAS/SK
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Aplastic Anemia Healthy Gifting Ideas for Diwali 

Recommended Reading
Unwanted ‘Ambulance Response’ Of Immune Cells Can Be Blocked
A collaborative study has found a new way to selectively block the ability of white blood cells to ....
Novel Mechanism Behind Autoimmunity Development Found
A new study from the National Institutes of Health (NIH) in the U.S. has led to the identification ....
Aplastic Anemia
Aplastic anemia (AA) is a term that refers to a condition where the body fails to produce enough blo...
Healthy Gifting Ideas for Diwali
Diwali, the festival of lights is round the corner. Take a fat free route when it comes to gifting t...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use