About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Discover Driving Force Behind Prostate Cancer

by Sheela Philomena on March 31, 2013 at 11:20 AM
Font : A-A+

 Scientists Discover Driving Force Behind Prostate Cancer

The existence of a cancer inducing DNA re-alignment in stem cells taken from human prostate cancers has been identified by researchers.

Professor Norman Maitland, Director of the YCR Cancer Research Unit, University of York, said that this discovery has marked a fundamental shift in our understanding of how solid cancers start.

Advertisement

He asserted that in blood cancers like leukaemia, DNA is rearranged during an event known as chromosomal translocation, which results in a mutant protein that drives cancer progression.

Maitland's team has found these genetic accidents in prostate cancer stem cells and have shown that they result in a specific cancer-associated gene within the cells called ERG being inappropriately activated.
Advertisement

It is believed that this activation triggers the stem cells to renew more often.

Maitland said that the cells become selfish by surviving outside normal controls that exist in the prostate and thrive at the expense of their neighbours, ensuring that the genetic accident becomes permanent and passed from generation to generation.

He added that this process appears to be essential for the initiation of prostate cancer.

The study has been published in Nature Communications.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
January is the Thyroid Awareness Month in 2022
Menstrual Disorders
Coffee May Help You Fight Endometrial Cancer
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Prostate Cancer Cancer and Homeopathy Trans-Urethral Resection of the Prostate Alcohol and Driving Prostate Cancer Facts Cancer Facts Cancer Tattoos A Body Art Prostate Cancer: Treatment Options Prostate Specific Antigen [PSA] 

Recommended Reading
Prostate Specific Antigen [PSA]
PSA blood test is specific to prostate gland but not necessarily a cancer specific test but is ......
Prostate Cancer Screening
PSA (Prostate Specific Antigen) test and Digital Rectal Examination are two tests that allow ......
Quiz on Prostate Cancer
Prostate cancer is fast gaining as a common cancer form among men; more threatening since its ......
Foods That Boost Men's Health
Heart Disease and Cancer are the major killers for men above the age of 40. Cholesterol lowering ......
Alcohol and Driving
Alcohol and driving do not mix. Drunken driving is the cause of many deaths in the world....
Prostate Cancer
This cancer affects men over the age of 50 years and screening with rectal examination and PSA can h...
Prostate Cancer: Treatment Options
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemothe...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)