Researchers Closer to Meningitis B Vaccine

Trials of meningitis B vaccine show promising results, say scientists.

After taking the drug, the test group generated antibodies that are active against 90 percent of strains in the meningitis B group affecting the United States and Europe.

Meningitis - Causes - Symptoms - Diagnosis - Treatment - FAQs
Meninges are the three layers of membrane that cover the brain and infection of the cerebrospinal fluid between them causes meningitis the disease of the meninges.

"Our data suggest that this vaccine is a promising and broadly protective meningococcal serogroup B vaccine candidate," said study lead author Peter Richmond from the University of Western Australia's School of Paediatrics and Child Health.

Meningitis, an inflammation of the lining around the brain and spinal cord, mostly targets teenagers -- with a fatality rate of between five percent and 14 percent.

Many survivors suffer permanent neurological damage and limb or hearing loss.

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Vaccines exist against types A and C meningitis, but none that is broadly effective against strains in serogroup B, mostly prevalent in industrialised nations.

Type A is the primary cause of epidemic meningitis in Africa.

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"The results showed that three doses produced an immune response, indicating protection, in 80 percent to 100 percent of adolescents," said a statement.

"Mild to moderate pain at the injection site was the most commonly reported side effect."

Novartis Reveals Development of New Meningitis Vaccine for Teens
Leading pharmaceutical giant Novartis revealed that it has developed a new vaccine that provides teenagers with full protection against meningitis B bacteria.

The authors said further trials must be held to determine the duration of vaccine protection.

"If additional studies show similar immunogenicity (the ability to produce an immune response) and tolerability, this vaccine might help to reduce the global burden of invasive meningococcal disease," said Richmond.

Source-AFP