A single dose of psilocybin induces changes in perception and mystical-type experience and significantly lowered levels of anxiety and depression.

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An active ingredient in magic mushrooms called psilocybin has been found to decrease negative mood in patients with life-threatening cancer.
Five weeks after receiving a dose of psilocybin sufficiently high to induce changes in perception and mystical-type experiences, patients reported significantly lower levels of anxiety and depression compared with patients that received a low dose of the drug. The positive effects on mood persisted in the patients at 6 month follow-up.
The authors suggest that a single dose of psilocybin may be sufficient to produce enduring decreases in negative mood in patients with a life-threatening cancer.
The study was presented at the annual meeting of the American College of Neuropsychopharmacology.
Source-Eurekalert
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