About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Polyphenols in Red Wine Reduce Risk of Cardiovascular Disease

by Savitha C Muppala on January 21, 2012 at 7:26 PM
Font : A-A+

 Polyphenols in Red Wine Reduce Risk of Cardiovascular Disease

The role of polyphenols in red wine in reducing the risk of cardiovascular disease has been clearly studied by scientists.

Observational epidemiologic studies relating wine and alcohol to health all suffer from the fact that they compare people who prefer certain beverages, but not the beverages themselves.

Advertisement

While there have been many intervention trials in animals, randomised trials in humans are less common. Randomised crossover trials, in which each subject receives all interventions in sequence, can be especially important as they tend to avoid baseline differences among subjects and can detect effects of different interventions with smaller numbers of subjects.

The new study, by Chiva-Blanch G et al, included 67 male volunteers in Spain who were considered to be at "high-risk" of cardiovascular disease on the basis of increased BMI, smoking, diabetes, hypertension, or other risk factors.
Advertisement

About one half of the individuals were taking ACE inhibitors, statins, aspirin, and oral hypoglycemic drugs, so the results of this study may be especially relevant for patients in the real world.

The subjects agreed to not consume any alcohol for a baseline period, then for three one-month periods consumed 30 grams per day of alcohol as red wine or as gin, or an equivalent amount of phenolics from dealcoholized red wine.

The polyphenol contents of the RW and the DRW interventions were the same. A very high degree of compliance of the subjects with the assigned interventions is evidenced by results of counting numbers of empty bottles of the intervention beverage returned, dietary records, urinary metabolites, etc.

Further, there is good evidence that there were no important changes between periods in diet or exercise habits. The effects of each intervention on a large number of adhesion molecules and chemokines that affect inflammation and relate to the development of vascular disease were evaluated.

The key results of the study were that both ethanol and nonalcoholic compounds in red wine have potentially protective effects that may reduce the risk of vascular disease.

"The phenolic content of red wine may modulate leukocyte adhesion molecules, whereas both ethanol and polyphenols of red wine may modulate soluble inflammatory mediators in patients at high risk of cardiovascular disease," the authors said.

The study has been published in the American Journal of Clinical Nutrition.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Top 10 Vitamin B12 Foods for Vegetarians - Slideshow
Targeted Screening Program Beneficial for Prostate Cancer Screening
Are Menopause Symptoms Troubling You?: Try these Options
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Anti-ageing and Benefits of Red Wine Bubbles and Brews - Alcohol Facts Malnutrition to Obesity - The Big Leap Anti-Aging Treatment with Vinotherapy or Wine Facials Nutrient Packed Pomegranate Christmas Feast, It’s always Grand with Cake and Wine 

Most Popular on Medindia

Drug - Food Interactions Pregnancy Confirmation Calculator Drug Interaction Checker Diaphragmatic Hernia Blood - Sugar Chart Find a Hospital Drug Side Effects Calculator Blood Donation - Recipients Calculate Ideal Weight for Infants Turmeric Powder - Health Benefits, Uses & Side Effects

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use