About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Oral Cavity Opens Up a New World for the Blind

by Medindia Content Team on October 30, 2007 at 1:27 PM
Font : A-A+

Oral Cavity Opens Up a New World for the Blind

Good news for those who have lost their eyesight because of injuries or burns. Researchers have found a new method of bringing back the sight by transplanting stem cells from one's own oral mucous. Results of the research are so far promising, say scientists.

Stem cells are primal cells found in all multicellular organisms and they have the ability to renew themselves through cell division. The cells can also differentiate into a diverse range of specialised cell types.

Advertisement

In the case of treatment of the eye, stem cells from the healthy eye are used for transplantation in the injured eye. If both the eyes are damaged, stem cells are taken from a donor. This is seen to cause infections, side effects on liver and kidney.

Patients also have to use drugs (immuno suppressants) for life long; the drugs cost about Rs 400 a day. City-based LV Prasad Eye Institute (LVPEI) has found an answer to this vexing issue for patients, and doctors too. The year-long research found an answer in the oral cavity.
Advertisement

LVPEI is close to commencing clinical trials on this new technique on patients very soon. The institute has been working on using stem cells for repairing the eyesight for the last four years. Several cases of partial and total blindness too are being handled using the stem cell research.

Stem cell scientist Yashoda Ghanekar and her team at LVPEI have developed the oral mucus solution that will throw light into the lives of two patients scheduled to undergo the transplant in a week.

'We have developed the technique over a year that could reconstruct ocular surface using stem cells from the patient's oral cavity. This technique will be useful for patients who have lost limbal stem cells from both eyes,' Ghanekar says. Currently, such patients undergo ocular surface reconstruction using limbal cells from donor eyes, and are seen to develop immune-related problems and also face side effects of immuno suppressants.

Though such a technique is in use in Japan, the team developed it sans feeder cells. Feeder cells are cells of animal origin that are cultured along with cells of interest. They promote growth of cells cultured along with them. However, they carry risks of producing unknown infections, particularly viral, in the recipients.

According to Geeta V Vemuganti, head of stem cell laboratory and director of ophthalmic pathology service at LVPEI, the institute has since 2001 transplanted stem cells on over 500 patients, and the success rate has been 70 per cent. Her team is now exploring the advantages of using synthetic scaffold instead of amniotic membrane as a sheet to grow stem cells on it.

Source: Medindia
RAM/C
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Tongue Abnormalities Oral Cancer Dental Check-Up Benefits of Coconut Oil Pulling 

Recommended Reading
Stem Cells - Fundamentals
Encyclopedia section of medindia gives general info about Stem Cells...
Stem Cell Therapy Could Provide Cure for AMD in Five Years
Scientists in the UK are teaming up for a groundbreaking surgical therapy that could cure ......
Benefits of Coconut Oil Pulling
Oil pulling is a type of oral therapy that cleanses the oral cavity by expelling toxins. This is an ...
Dental Check-Up
It is commonly recommended that you visit the dentist twice a year to clean your teeth and gums and ...
Oral Cancer
Oral cancer is a cancer that develops in any part of the mouth. It is more common in men over 40....
Tongue Abnormalities
Tongue is the only muscle that is attached to only one end. The abnormalities of the tongue include ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use