About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Non-aspirin NSAIDs Help Prevent Recurrence of Colorectal Cancer

by Sheela Philomena on December 20, 2016 at 5:32 PM
Font : A-A+

Non-aspirin NSAIDs Help Prevent Recurrence of Colorectal Cancer

Non-aspirin NSAIDs (e.g., ibuprofen) work better than aspirin to prevent the recurrence of advanced neoplasia (polyps that are the precursor of colorectal cancer) after polyp removal, reveals research published in BMJ.

According to the World Cancer Research Fund, colorectal cancer is the third most common cancer in the world. In the U.S., more than one-third of people who develop colorectal cancer will die of the disease, with most of those cancers arising from advanced neoplasia (also known as advanced adenomas or adenomatous polyps).

Advertisement


In the paper, they say that due to most colorectal cancers developing from this type of polyps, preventing them is a good proxy for colorectal cancer prevention.

"Approximately 85 percent of all colorectal cancers are thought to result from untreated adenomatous polyps," says M. Hassan Murad, M.D., a clinical epidemiologist and preventive medicine physician at Mayo Clinic, and the study's senior author. "If we can find a way to stop their growth, we could prevent a majority of these cases."
Advertisement

"We knew that aspirin and other NSAIDs have a protective effect, and that a number of other nutritional supplements have also been studied for their effectiveness in preventing cancer," says Dr. Murad. "What we didn't know is how they compared to each other."

The team conducted a meta-analysis (a statistical research method that involves combining data from multiple studies to obtain a single consolidated observation) of clinical trial data from 15 randomized control trials, reviewing information from 12,234 patients. These studies included low- and high-dose aspirin therapy, calcium, vitamin D and folic acid, and compared them each alone or in various combinations.

However, because of some of the other health risks of nonaspirin NSAIDs, they may not be the best choice for everyone.

Aspirin had nearly as good of results, with much less additional risk. Dr. Murad and his colleagues cautioned that, although low-dose aspirin was ranked second in preventive capabilities, "the excess benefit over risk might therefore be favorable for many patients."

"It is important that patients and doctors have a discussion on the various risks and benefits of any medication or other therapy," says Dr. Murad. "While a research publication may contain promising findings, it is generalized information, and each individual is different. So their care will be individualized, as well."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Diet and Oral Health: The Sugary Connection May Become Sour
World AIDS Day 2022 - Equalize!
Test Your Knowledge on Sugar Intake and Oral Health
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Colo-rectal cancer - Management Colorectal Cancer Cancer Facts Cancer Tattoos A Body Art Colon Polyps Colorectal Cancer Screening Colorectal Cancer Screening with Colonoscopy Colorectal Cancer Screening with Double-Contrast Barium Enema 

Most Popular on Medindia

Sanatogen Blood Donation - Recipients Find a Doctor Drug Side Effects Calculator Selfie Addiction Calculator How to Reduce School Bag Weight - Simple Tips Noscaphene (Noscapine) Drug Interaction Checker Vent Forte (Theophylline) Blood - Sugar Chart
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Non-aspirin NSAIDs Help Prevent Recurrence of Colorectal Cancer Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests