In patients with rheumatoid arthritis, non-invasive stimulation at the external ear was found to improve disease symptoms, revealed scientists at Feinstein Institute for Medical Research collaborated with counterparts from Academic Medical Center at University of Amsterdam in the Netherlands.
These findings were first published today in Bioelectronic Medicine. An emerging field of science, bioelectronic medicine draws on neuroscience, focuses on molecular targets, and deploys bioengineering to tap into the nervous system to treat disease and injury without the use of pharmaceuticals.
RA is a chronic inflammatory disease, which is characterized by pain, swelling and stiffness of joints. It affects around 1.3 million people in the United States and costs tens of billions of dollars annually to treat. Commonly, signs and symptoms of this condition are treated using synthetic and biological antirheumatic drugs. However, these medications can result in side effects and may not be effective in all RA patients.
"Our primary objective was to observe if a non-invasive treatment using an external device will be effective in improving disease severity of rheumatoid arthritis that continues to plague more than one million across the country each year," Dr. Chavan said. "We are pleased to observe that this novel bioelectronic treatment significantly reduces swelling and inflammation associated with RA."