A new set of compounds identified by scientists may prove to be a good treatment against multiple sclerosis.
Unlike existing MS therapies that suppress the immune system, the compounds boost a population of progenitor cells that can in turn repair MS-damaged nerve fibers.
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One of the newly identified compounds, a Parkinson's disease drug called benztropine, was highly effective in treating a standard model of MS in mice, both alone and in combination with existing MS therapies.
"We're excited about these results, and are now considering how to design an initial clinical trial," Luke L. Lairson, an assistant professor of Chemistry at TSRI and senior author of the study, said.
![Neuropsychological Problems Linked to Regional Gray Matter Atrophy in Multiple Sclerosis]( "Neuropsychological Problems Linked to Regional Gray Matter Atrophy in Multiple Sclerosis")
Previous research has indicated that gray matter atrophy is extensive in multiple sclerosis and cognitive deficits are frequently encountered in the condition.
Lairson cautioned that benztropine is a drug with dose-related adverse side effects, and has yet to be proven effective at a safe dose in human MS patients.
"People shouldn't start using it off-label for MS," he said.
The study is published online in the journal Nature.
Source: ANI
Neuropsychological Problems Linked to Regional Gray Matter Atrophy in Multiple Sclerosis
Previous research has indicated that gray matter atrophy is extensive in multiple sclerosis and cognitive deficits are frequently encountered in the condition.
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Lairson cautioned that benztropine is a drug with dose-related adverse side effects, and has yet to be proven effective at a safe dose in human MS patients.
"People shouldn't start using it off-label for MS," he said.
The study is published online in the journal Nature.
Source: ANI
Multiple Sclerosis Appears to Originate in Different Part of Brain: Study
The cause of multiple sclerosis, a debilitating disease that affects up to a half million people in the US, has confounded researchers and medical professionals for generations.
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