Over 600 people who took an HIV prevention pill for more than 2 years were found to be free from the virus even in high-risk environments, said researchers.
The study conducted at Kaiser Permanente in San Francisco involved more than 600 high-risk individuals, most of whom were men who have sex with men. These individuals were healthy at the time of enrollment and were put on a daily regimen of a blue pill called Truvada as a Pre-exposure Prophylaxis (PrEP).
This study is "the first to extend the understanding of the use of PrEP in a real-world setting and suggests that the treatment may prevent new HIV infections even in a high-risk setting," said Lead Author Jonathan Volk, a Physician and Epidemiologist at Kaiser Permanente San Francisco Medical Center.
In the study, 100 percent of the participants remained HIV-free. Not a single person in the study became infected while on the drug during the study period that included 2.5 years of observation.
"Tremendously good news," University of California-San Francisco researchers Kimberly A. Koester and Robert M. Grant said in a commentary accompanying the study published in the journal Clinical Infectious Diseases
. They said it was not clear from the study if the reported rate of sexually transmitted infections in the study is an increase or not and that further investigation is needed.
They recommended that Truvada be combined with a parallel plan to prevent other STIs which may include the use of condoms, more frequent testing and discussions with prospective partners. There are several dozen other ongoing clinical trials worldwide using Truvada in different populations.