New Discovery About Diabetes may Reduce the Risk of Organ Failure

Identifying how diabetes affects stem cells residing in muscle to form fat and connective tissue has major clinical perspectives, according to researchers from Aarhus University and the Steno Diabetes Center Aarhus.

Researchers have studied how type 2 diabetes alters the skeletal muscles. They discovered that both fibrosis and fatty tissue are formed in the muscles.

Metformin - Diabetes Drug with New Therapeutic Uses
Metformin, a century old anti-diabetic drug used commonly to bring down blood sugar levels has other therapeutic uses like treating PCOS, aging and obesity.

‘Human skeletal muscle fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients.’

Tweet it Now

Unhealthy skeletal muscle with an accumulation of connective tissue (fibrosis) and fat cells (called adipogenesis in medicine) damage the muscle’s function.

Researchers also uncovered how gene expression occurs in an unhealthy cell compared to a healthy cell. Once they had identified the cells, they examined how the cells changed in a person with type 2 diabetes.

According to the researcher, because the same cells are present all over the body, we can envision that they are also responsible for the accumulation of fat and scar tissue in other organs.

Diabetes Diet Plan
Diet plays a significant role in controlling diabetes. Most cases of diabetes are preventable with healthy lifestyle changes.

This is to say that they probably play a major role in connection with e.g. heart failure, kidney failure, or liver failure in people.

In the study, researchers have examined how the treatment of diabetes with the medicine metformin, which is typically the initial choice for type 2 diabetics, affects the development of fibrosis-forming and fat-forming cells.

Diabetes and Dental Health
The oral health preventive strategies in individuals at risk for diabetes are important because they play a key role in oral diseases that affect dental care.

Their studies showed that the treatment causes the cells to divide less, which may result in less accumulation of fat and scar tissue in the muscles.

The research results, which have been published in the scientific journal Cell Metabolism, show that undesirable cell development may occur early in the onset of the disease.

Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most common lifestyle habits that cause chronic diseases such as obesity, hypertension, diabetes mellitus, cancer and cardiovascular disease.

This could prevent complications such as heart failure, renal failure, thrombosis, or that different organs stop functioning because they’ve been overloaded for some time and have developed scar tissue and fat deposits.

Source-Medindia