A new study has found that women who eat high-fat diet before and during pregnancy more likely to give birth to babies with higher fat mass and smaller livers.

"One of the key findings here is that the offspring are born with a marked shift in body composition, away from lean mass and toward fat mass, prior to any dietary exposure in the offspring themselves," said principal investigator Stephanie M. Krasnow, Ph.D., a scientist in the Pape Family Pediatric Research Institute at OHSU Doernbecher Children's Hospital.
In the study, Krasnow and colleagues fed female mice either a low-fat or high-fat diet for six months, and allowed them to mate with male mice after 4, 12 and 23 weeks.
The females who ate a high-fat diet gained more body weight and had a higher fat mass than the females who ate a low-fat diet.
And on the day of birth, babies born to females who had consumed a high-fat food had more body fat, less lean mass, and smaller livers than the newborns of females that consumed low-fat food.
The findings have been published online in the American Journal of Physiology and Endocrinology Metabolism.
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