Microbiome Changes Linked to Colorectal Cancer Detection

by Colleen Fleiss on  June 16, 2019 at 1:11 AM Cancer News
RSS Email Print This Page Comment bookmark
Font : A-A+

Increases in specific microbiome organisms were associated with colorectal cancer such as intramucosal carcinomas and polypoid adenomas, said Osaka University researchers. Their results, recently published in Nature Medicine Letters, reveal that these specific markers could help distinguish cases of colorectal cancer from healthy samples.
Microbiome Changes Linked to Colorectal Cancer Detection
Microbiome Changes Linked to Colorectal Cancer Detection

The gut has a population of organisms that live within in it, called the gut microbiome, which are linked to human health and disease. Recent studies have shown that assessing the genetic changes in fecal samples can accurately reflect the status of the gut microbiome, and may be useful for the early diagnosis of diseases.

Show Full Article


"We believe that colorectal cancer is fundamentally not only a genetic but also a microbial disease," says one of the study's corresponding authors, Shinichi Yachida. "Our results show that changes in the gut microbiome are present at the very early stages of colorectal cancer development, which could potentially provide vital diagnostic and causative clues for this disease."

Colorectal cancer, the third most prevalent cancer globally, is a relatively slow-moving disease--meaning it takes a long period of time before reaching its final, fatal stages. Therefore, early detection is crucial to ensuring effective treatment. The researchers used fecal samples from a little over 600 patients who underwent colonoscopy to assess the characteristics of their gut microbiota and how they relate to colorectal cancer.

"Future studies will focus on the relationship between the gut microbiome and tumor characteristics in individual patients with colorectal cancer. This will help us understand the roles of the microbiome in the development of colorectal cancer,"says the second corresponding author, Takuji Yamada.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

Recommended Reading

More News on:

Cancer and Homeopathy Colo-rectal cancer - Management Colorectal Cancer Cancer Facts Cancer Tattoos A Body Art Colon Polyps Colorectal Cancer Screening Colorectal Cancer Screening with Colonoscopy Colorectal Cancer Screening with Double-Contrast Barium Enema 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive