About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Link Between Type 2 Diabetes and COPD Discovered

by Colleen Fleiss on April 25, 2019 at 6:29 AM
Font : A-A+

Link Between Type 2 Diabetes and COPD Discovered

The relationship between chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) has been revealed by a team of researchers from USA, led by Chaitanya Mamillapalli, at the Endocrinology department at the Springfield Clinic in Illinois. The findings of the study are published in Current Respiratory Medicine Reviews.

Chronic obstructive pulmonary disease (COPD) is characterized by a chronic airflow obstruction that is associated with severe global mortality and morbidity.

Advertisement


According to the review, the estimated global prevalence of COPD in 2010 is 11.7% corresponding to 384 million affected cases and is projected to be the third leading cause of death globally by 2030. Type 2 diabetes (T2 DM) is a metabolic disease associated with hyperglycemia, insulin resistance, and relative insulin deficiency.

The global prevalence of T2 DM has increased dramatically in the last two decades, with an estimated 382 million people diagnosed in 2013 and the incidence is rapidly growing. It is projected to affect 592 million people by 2035. COPD is increasingly being recognized as a systemic inflammatory condition affecting more than just the lung. Comorbid chronic health conditions associated with COPD have poorer outcomes and require complex personalized therapeutic intervention approach.
Advertisement

COPD is being increasingly recognized as a risk factor for the development of T2 DM through different mechanisms including systemic inflammation, obesity, hypoxia and use of corticosteroids.

T2 DM and COPD are both expected to be among the top ten leading causes of mortality and burden of disease worldwide by 2030. There are limited clinical studies addressing the management of patients who have T2 DM and COPD.

Presently, management options are geared towards symptomatic management but do not address the underlying cause of these diseases. It would be ideal to target treatments to address the underlying systemic inflammation, but no such therapeutic agents are available yet. The standard of care respiratory management with timely treatment of COPD exacerbations, flu vaccination, antibiotic use can result in the reduction of oxidative stress and systemic inflammation, which will, in turn, will reduce insulin resistance and optimize glucose control in T2 DM patients.

Achieving optimal glucose control is crucial in patients with coexistent T2 DM and COPD, to prevent adverse outcomes in COPD patients and diabetic complications related to T2 DM. The researchers also review the safety and outcome data for various diabetes treatment agents such as metformin, thiazolidinediones, Glucagon like peptide -1 analogues and insulin use in COPD patients.

Given the overwhelming evidence of the association between the COPD and T2 DM, their intertwined pathologies and the impact on the prognosis, it is important for the endocrinologist to measure lung function in T2 DM patients and for pulmonologists to screen for T2 DM in COPD patients. The team of researchers believes that this collaborative partnership is crucial for improving the outcomes in patients. The team also agrees additional research is required to improve our knowledge about the relationship between COPD and T2 DM, to help with providing better care with these two common disorders.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Ways to Manage Stress during COVID-19 Pandemic
Can Adjusting Fatty Acid Intake Improve Mood in Bipolar Disorder Patients?
Insulin Resistance Doubles the Risk of Major Depressive Disorder
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diabetic Retinopathy Diabetes Diabetic Diet Otitis Media Diabetes - Essentials Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Diabetes and Exercise Stress Relief Through Alternative Medicine Stress and the Gender Divide 

Recommended Reading
Diabetes
A comprehensive article on diabetes - both Type 1 and Type 2 diabetes, including : causes, signs, .....
Risk of Vascular Complications Lower in Patients With Mild Hyperglycemia and Genetic Mutation
A new study published in JAMA suggests that risk of clinically significant vascular complications .....
Diabetes Risk Assessment Calculator
Almost one-third of the people are unaware of the risk factors of diabetes. Find out if you run the ...
Quiz on Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease affects millions of people worldwide and is responsible ......
Diabetes - Essentials
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels a...
Diabetes - Self-Monitoring of Blood Glucose (SMBG)
Self-Monitoring Of Blood Glucose (SMBG) is one of the greatest advancements in the management of Di...
Diabetes and Exercise
Regular exercise especially in type II diabetes not only helps reduce the sugar but also reduces the...
Diabetic Diet
The diabetic diet most often recommended is high in dietary fiber (especially soluble fiber) and nut...
Diabetic Retinopathy
The term ‘diabetic retinopathy’ refers to changes in the retina which often occur in people with ......
Insulin Delivery Devices
Insulin delivery devices have evolved drastically since their invention in 1922. They are all aimed ...
Otitis Media
Middle ear infection, or otitis media, is a common type of infection that may or may not accompany t...
Stress and the Gender Divide
Stress has become entwined in the current lifestyle of a young working couple and has resulted in th...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use