Byotrol, an antimicrobial technology developed by a Manchester-based paint firm, has a polymer-based structure, which enables it to kill bacteria, like MSRA, days after being first applied.
The polymer is said to create a surface tension effect, which operates like a flytrap that literally tears apart the bacteria when they come into contact.
"These are very impressive results. Our study has shown a reduction of one third in levels of MRSA in the ward when the new disinfectant was compared with the gold-standard NHS bleach-based cleaning agent," the Telegraph quoted Dr Andy Dodgson, consultant microbiologist at the MRI who led the trial as saying.
"The new disinfectant has a clear role to play in helping hospitals in the battle to control HCASIs. Cutting the level of pathogens on the wards rescues the risk to patients of picking up an infection.
"The demonstration of a residual antibacterial effect is a major new discovery which will be an additional weapon for the NHS in the fight against superbugs," he added.
Stephen Falder, the scientist who invented Byotrol, said: "I suppose you could say this is a prevention for superbugs that almost never happened. I began developing it as a protection to stop mould on paints. It grew from there."
The study will be published in British Journal of Infection Control.