Intermittent fasting may regulate blood sugar (glucose) levels even when accompanied by little or no weight loss, finds a new study published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.
Intermittent fasting is a type of eating diet plan cycling through periods of normal eating and fasting. In people with mild obesity, intermittent fasting has been found effective for weight loss and an associated reduction of high blood pressure and cholesterol. However, less is known about its effects on people who are extremely obese and whose obesity is caused more by genetics than by lifestyle.
Researchers examined mice with genetic obesity and high insulin and glucose levels. These mice do not produce the appetite-regulating hormone leptin. Previous research suggests that impaired leptin signaling can be a primary cause for obesity in humans. The obese mice followed an alternate day feeding schedule for two and a half weeks, with unlimited access to food on feeding days.