High Levels of Air Pollution Increase Breast Cancer Risk

by Hannah Joy on  April 6, 2017 at 11:02 AM Cancer News
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Women living in areas where air pollution is high are at a risk for developing breast cancer. Increased levels of fine particles in the air increase a woman's chance of having dense breasts, reveals a new study.
 High Levels of Air Pollution Increase Breast Cancer Risk
High Levels of Air Pollution Increase Breast Cancer Risk

Nearly 280,000 women in the United States have participated in the study that was published in the open access Journal Breast Cancer Research.

The study, the largest of its kind to investigate the association of air pollution with breast density, found that for every one unit increase in fine particle concentration (PM2.5), a woman's chance of having dense breasts was increased by 4%.

Women with dense breasts were around 20% more likely to have been exposed to higher concentrations of PM2.5. Conversely, women with less dense, or breasts with more fatty tissue, were 12% less likely to have been exposed to high concentrations of PM2.5.

Breast density is measured by mammography and reflects the relative amounts of different tissue types in the breast.

Breasts with a majority of fatty tissue are easier to interpret by mammography and so abnormalities become easier to spot. Dense breasts contain a higher percentage of fibroglandular tissue which obscures mammography and makes it difficult to identity abnormalities such as a breast tumour.

Dr Lusine Yaghjyan, lead author from the University of Florida, said: "Our findings suggest that previously reported geographic variation in breast density could, in part, be explained by different air pollution patterns in urban and rural areas. Breast density is a well-established and strong breast cancer risk factor so future studies are warranted to determine if the observed associations are causal, which if confirmed may have implications for risk prevention."

The researchers also looked at the association between ozone exposure and breast density among the 280,000 women included in the study. They found that every one unit increase in ozone concentration was associated with a 3% lower chance of having dense breasts.

Dr Yaghjyan explained: "We found a positive association between fine particle concentration exposure and breast density but an inverse association between ozone exposure and breast density. This is an intriguing result that warrants further investigation to unpick any possible biological mechanism that might cause ozone exposure to reduce a woman's chance of having dense breasts."

Chemical constituents of PM2.5 air pollution are known to include pollutants that have endocrine disrupting properties.

According to researchers, although causation cannot be established in this observational study, due to uncontrolled factors, these pollutants could potentially influence breast density by interfering with growth of cells in the breast and increasing the relative amount of fibroglandular tissue.

Women for this study were selected from the Breast Cancer Surveillance Consortium, a population-based cohort of women undergoing mammographic screening across the United States.

Mammographic data, including breast density, was included from women who were screened between 2001 and 2009. Breast density was measured using the BI-RADS system, a method developed by the American College of Radiology to standardize beast density measurements.

Air pollution data corresponding to the areas where the women lived before or around the time of their mammogram was obtained from the United States Environment Protection Agency.

Source: Eurekalert

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OM SRI GANESHAYA NAMAHA Good day, by wearing suitable masks and covers and specially designed dresses even in a highly polluted area the air can be filtered and all can breathe fresh oxygenated air. Further more along with every breath intaken , all cancer patients can also intake Ayurvedic or other specially designed cancer cell fighting medicine just like Vicks inhaler is taken for cold.This way the fight against cancer is 24x7 and 365 till the disease is completely destroyed.Chemical reactions are faster in gaseous state because of high volatility so the fight against the disease source will also be faster this way.This approach can be used for cure for all diseases so that the fight against the disease is continuous.Every input to the patient including food can be screened by clever monitoring devices to determine risk of dangers upon incorrect input.even normal people can scan the food in taken using a clever gadget like fitted on the face like a spectacle for a healthy life style. By equipping the patient with clever disease monitoring devices, the fight against the disease can be controlled in a better way so that the patient lives a very healthy life thanking Good God for all blessings. SARVAM SRI KRISHNARPANAMASTU MASTU


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