About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Hidden Differences in Neuronal Circuits may Explain Variation in Brain Injury Outcomes

by Bidita Debnath on July 19, 2014 at 11:42 PM
Font : A-A+

 Hidden Differences in Neuronal Circuits may Explain Variation in Brain Injury Outcomes

A team of researchers have discovered that hidden differences in the properties of neural circuits can account for whether animals are behaviorally susceptible to brain injury.

The research took place at the Neuroscience Institute at Georgia State University. These results could have implications for the treatment of brain trauma.

Advertisement

People vary in their responses to stroke and trauma, which impedes the ability of physicians to predict patient outcomes. Damage to the brain and nervous system can lead to severe disabilities, including epilepsy and cognitive impairment.

If doctors could predict outcomes with greater accuracy, patients might benefit from more tailored treatments. Unfortunately, the complexity of the human brain hinders efforts to explain why similar brain damage can affect each person differently.
Advertisement

The researchers used a unique research animal, a sea slug called Tritonia diomedea, to study this question. This animal was used because unlike humans, it has a small number of neurons and its behavior is simple. Despite this simplicity, the animals varied in how neurons were connected.

Under normal conditions, this variability did not matter to the animals' behavior, but when a major pathway in the brain was severed, some of the animals showed little behavioral deficit, while others could not produce the behavior being studied. Remarkably, the researchers could artificially rewire the neural circuit using computer-generated connections and make animals susceptible or invulnerable to the injury.

"This study is important in light of the current Obama BRAIN initiative, which seeks to map all of the connections in the human brain," said Georgia State professor, Paul Katz, who led the research project. "It shows that even in a simple brain, small differences that have no effect under normal conditions, have major implications when the nervous system is challenged by injury or trauma."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Health Benefits of Sea Buckthorn
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Athletes Foot Parkinsons Disease Parkinsons Disease Surgical Treatment Head Injury Brain Brain Facts Aphasia Ataxia Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) 

Recommended Reading
Mild Traumatic Brain Injury may Cause Brain Damage
A new study published in Neurology finds even mild traumatic brain injury may cause brain damage, .....
Variations in Neuronal Networks may Point Out to Traumatic Brain Injury Outcomes
The hidden differences between the properties of neural circuits may help determine if animals are ....
Traumatic Brain Injury Linked to an Increased Risk of Dementia
Older veterans having suffered traumatic brain injury are at a 60% higher risk of developing ......
Coping With Personality Changes in Acquired Brain Injury may Get Easier
Individuals affected by brain injuries may struggle with associated personality changes, and ......
Aphasia
Aphasia is a condition where the patient has a language disorder. The patient has problems with comp...
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Athletes Foot
Athlete’s foot (tinea pedis/ringworm of the foot) is a fungal infection of the feet....
Head Injury
Head injury or traumatic brain injury is a leading cause of disability among children and young adul...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use